Embryo Selection and Frontier Genomics with Dr. Alex Young – Manifold #111
Dr. Alex Young, a statistical geneticist and assistant professor in the Human Genetics department at UCLA, joins Steve Hsu to discuss the cutting edge of genomic prediction. They cover his research on polygenic embryo screening in IVF (including the ImputePGTA method), family-based DNA analysis, missing heritability, and the implications of polygenic scores for traits like education and disease. Alex also discusses his recent battles with cancer.
Chapter Markers:
(00:00) - Alex Young Bio
(06:36) - Biobank Era Genetics
(10:49) - Missing Heritability Debate
(27:18) - Embryo Selection Controversy
(50:32) - Embryo Selection Backlash
(53:42) - Mexico City Admixture Study
(01:00:13) - Censorship Via Data Access Control
(01:05:02) - Battle With Cancer and Circulating Tumor DNA (ctDNA)
Audio-only version and transcript:
https://www.manifold1.com/episodes/embryo-selection-and-frontier-genomics-with-dr-alex-young-111


Video link should work now - apologies
Hey Steve, when I go to watch the video it says,
"This video is private
If the owner of this video has granted you access, please sign in."
Not sure if others are having problems but maybe you need to unprivate it?