If mapping the genetic architecture of intelligence only needs ~$100m, why don't you do it? You know both a lot of billionaires and genomics experts. Wouldn't it be satisfying the shut the blank-slatists up once and for all?
On genome engineering: instead of editing, do 46x whole-chromosome selection from sperm. Chromosome transfer in human cells, even two chromosomes in mice has been done. The sperm might come from edited tissue culture, but very high selection ratios are possible from natural sperm, too. If the subject is DNA sequenced, fluorescent tags for their less-desirable alleles on a chromosome can be found, all chromosomes of that type in the semen with those alleles will light up, allowing separating the others of that type with good genes by electrophoresis. This could allow elimination of genetic load in one generation, with very high effective selection factors raised to the power of the number of chromosomes thus selected. Could be of agricultural value before potential human use.
Hi Steve, really enjoyed the episode, as always, is there a new discord link?
https://discord.gg/jNevGNTJ
To create a Discord invite link that doesn’t expire in 7 days, you need to adjust the expiration settings when creating the invite:
1. Click on your server name or a target channel
2. Select “Invite”
3. Click on “Edit invite link” or the gear/settings icon
4. Under “Expire after,” change it from “7 days” to “Never”
5. Click “Save” or “Generate a New Link”
thanks steve!
If mapping the genetic architecture of intelligence only needs ~$100m, why don't you do it? You know both a lot of billionaires and genomics experts. Wouldn't it be satisfying the shut the blank-slatists up once and for all?
On genome engineering: instead of editing, do 46x whole-chromosome selection from sperm. Chromosome transfer in human cells, even two chromosomes in mice has been done. The sperm might come from edited tissue culture, but very high selection ratios are possible from natural sperm, too. If the subject is DNA sequenced, fluorescent tags for their less-desirable alleles on a chromosome can be found, all chromosomes of that type in the semen with those alleles will light up, allowing separating the others of that type with good genes by electrophoresis. This could allow elimination of genetic load in one generation, with very high effective selection factors raised to the power of the number of chromosomes thus selected. Could be of agricultural value before potential human use.
hi steve, discord link says "Invite Invalid"
Sorry! This is good for 7 days: https://discord.gg/dvcHS6NX